The average bus between Manchester and St. Louis takes 8h 37m and the fastest bus takes 8h 15m. The bus service runs several times per day from Manchester to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Manchester and St. Louis. The earliest departure is at 12:20 AM at night, and the last departure from Manchester is at 7:40 AM which arrives into St. Louis at 3:55 PM. All services require a transfer, and take on average 8h 37m. The schedules shown below are for the next available departures.
Want to know about travelling from Manchester to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manchester to St. Louis. However, there are services departing from Manchester station and arriving at St. Louis station via Nashville Bus Station station. The journey, including transfers, takes approximately 8h 37m.
Manchester to St. Louis bus services, operated by Greyhound USA, depart from Manchester station.
Manchester to St. Louis bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Book your Manchester to St. Louis bus tickets online with Greyhound USA and Flixbus USA.
The distance between Manchester and St. Louis is 505.2 km. The road distance is 612 km.
You can take a bus from Manchester to St Louis Bus Station via Nashville Bus Station in around 8h 55m.
