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Manchester to Hyannis buses

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Trip Overview

The average bus between Manchester and Hyannis takes 13h 4m and the fastest bus takes 9h 10m. The bus service runs several times per day from Manchester to Hyannis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

13h 4m
Duration
310 mi
Distance
$78
Average price
Twice daily
Frequency

Manchester to Hyannis bus times

Buses run twice daily between Manchester and Hyannis. The earliest departure is at 8:05 AM in the morning, and the last departure from Manchester is at 4:25 PM which arrives into Hyannis at 3:15 PM. All services require a transfer at Albany Bus Terminal, NY and take an average of 13h 4m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

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    Vermont TranslinesGreyhound USAPlymouth & Brockton9h 10m • 2 changes
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    Arrives next day

    Vermont TranslinesGreyhound USAPlymouth & Brockton22h 50m • 2 changes

Departing Friday, November 13, 2026

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    Vermont TranslinesGreyhound USAPlymouth & Brockton9h 10m • 2 changes
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    Arrives next day

    Vermont TranslinesFlixbus USAPlymouth & Brockton9h 10m • 2 changes

Departing Saturday, November 14, 2026

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    Vermont TranslinesGreyhound USAPlymouth & Brockton9h 10m • 2 changes
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    Arrives next day

    Vermont TranslinesGreyhound USAPlymouth & Brockton22h 50m • 2 changes

Departing Sunday, November 15, 2026

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    Vermont TranslinesGreyhound USAPlymouth & Brockton9h 10m • 2 changes
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    Arrives next day

    Vermont TranslinesFlixbus USAPlymouth & Brockton9h 10m • 2 changes

Departing Monday, November 16, 2026

  •  → 

    Vermont TranslinesGreyhound USAPlymouth & Brockton9h 10m • 2 changes
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    Arrives next day

    Vermont TranslinesGreyhound USAPlymouth & Brockton22h 50m • 2 changes

Departing Tuesday, November 17, 2026

  •  → 

    Vermont TranslinesGreyhound USAPlymouth & Brockton9h 10m • 2 changes
  •  → 

    Arrives next day

    Vermont TranslinesFlixbus USAPlymouth & Brockton9h 10m • 2 changes

Departing Wednesday, November 18, 2026

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    Vermont TranslinesGreyhound USAPlymouth & Brockton9h 10m • 2 changes

Frequently asked questions

Want to know about travelling from Manchester to Hyannis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Manchester to Hyannis.ExpandLaunch map view
  • Distance: 310.5 mi
  • Duration: 13h 4m

What companies run services between Manchester, VT, USA and Hyannis, MA, USA?

You can take a bus from Bus Parking Area Manchester to Hyannis Transportation Center via Albany Bus Terminal, NY, Boston, and Boston South Buses in around 9h 2m.

Operators