The average bus between Manchester and Aylesbury takes 5h 25m and the fastest bus takes 4h 18m. The bus service runs several times per day from Manchester to Aylesbury. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Manchester and Aylesbury. The earliest departure is at 2:45 AM at night, and the last departure from Manchester is at 11:40 PM which arrives into Aylesbury at 8:03 AM. All services require a transfer at Milton Keynes Coachway and take an average of 5h 25m. The schedules shown below are for the next available departures.


5h 49m • 2 changes


4h 33m • 2 changes


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5h 23m • 2 changes


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4h 33m • 2 changes


6h 3m • 2 changes


5h 23m • 2 changes


5h 49m • 2 changes


4h 33m • 2 changes


6h 3m • 2 changes


5h 23m • 2 changes


5h 49m • 2 changes


4h 33m • 2 changes


6h 3m • 2 changes


5h 23m • 2 changes


5h 49m • 2 changes


5h 8m • 2 changes


5h 33m • 2 changes


5h 3m • 2 changes
Want to know about travelling from Manchester to Aylesbury? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manchester to Aylesbury. However, there are services departing from Manchester station and arriving at Aylesbury station via Milton Keynes Coachway. The journey, including transfers, takes approximately 5h 25m.
Manchester to Aylesbury bus services, operated by National Express, depart from Manchester Central Coach Station.
Manchester to Aylesbury bus services, operated by National Express, arrive at Milton Keynes Coachway station.
Book your Manchester to Aylesbury bus tickets online with National Express, Arriva UK and 2 other operators.
The distance between Manchester and Aylesbury is 208.5 km. The road distance is 282 km.
National Express operates a bus from Manchester Central Coach Station to Milton Keynes Coachway every 30 minutes. Tickets cost £28–70 and the journey takes 4h.