The average bus between Manchester and Aylesbury takes 5h 21m and the fastest bus takes 4h 18m. The bus service runs several times per day from Manchester to Aylesbury. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Manchester and Aylesbury. The earliest departure is at 2:45 AM at night, and the last departure from Manchester is at 11:40 PM which arrives into Aylesbury at 6:45 AM. All services require a transfer at Milton Keynes Coachway and take an average of 5h 21m. The schedules shown below are for the next available departures.


5h 50m • 2 changes

4h 33m • 2 changes

6h 3m • 2 changes

4h 48m • 2 changes

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4h 33m • 2 changes

6h 3m • 2 changes

4h 48m • 2 changes

5h 50m • 2 changes

5h 8m • 2 changes

5h 3m • 2 changes

4h 43m • 2 changes

4h 38m • 2 changes

4h 43m • 2 changes

4h 28m • 2 changes

5h 23m • 2 changes

5h 50m • 2 changes

4h 33m • 2 changes

6h 3m • 2 changes

4h 48m • 2 changesWant to know about travelling from Manchester to Aylesbury? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manchester to Aylesbury. However, there are services departing from Manchester station and arriving at Aylesbury station via Milton Keynes Coachway. The journey, including transfers, takes approximately 5h 21m.
Manchester to Aylesbury bus services, operated by National Express, depart from Manchester Central Coach Station.
Manchester to Aylesbury bus services, operated by National Express, arrive at Milton Keynes Coachway station.
The distance between Manchester and Aylesbury is 208.5 km. The road distance is 282 km.
National Express operates a bus from Manchester Central Coach Station to Milton Keynes Coachway hourly. Tickets cost £29–70 and the journey takes 4h.