The average bus between Manchester and Downing Street takes 5h 21m and the fastest bus takes 4h 22m. There is a bus service every few hours from Manchester to Downing Street. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Manchester and Downing Street. The earliest departure is at 2:45 AM at night, and the last departure from Manchester is at 7:30 PM which arrives into Downing Street at 11:59 PM. All services require a transfer at Finchley Road / O2 Centre and take an average of 5h 21m. The schedules shown below are for the next available departures.

5h 14m • 1 change

5h 6m • 1 change

6h 10m • 1 change

5h • 1 change

6h 4m • 1 change

5h 24m • 1 change

5h 19m • 1 change

5h 23m • 1 change

5h 53m • 1 change

4h 47m • 1 change

4h 55m • 1 change

5h 9m • 1 change

5h 45m • 1 change

4h 56m • 1 change

4h 52m • 1 change

5h 16m • 1 change
Want to know about travelling from Manchester to Downing Street? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manchester to Downing Street. However, there are services departing from Manchester station and arriving at Downing Street station via Finchley Road / O2 Centre. The journey, including transfers, takes approximately 5h 21m.
Manchester to Downing Street bus services, operated by National Express, depart from Shudehill Interchange station.
Manchester to Downing Street bus services, operated by National Express, arrive at Finchley Road / O2 Centre station.
The distance between Manchester and Downing Street is 262.2 km. The road distance is 326 km.
FlixBus operates a bus from Shudehill Interchange to Finchley Road / O2 Centre hourly. Tickets cost £21–35 and the journey takes 4h 35m.