The average bus between Manchester and Harley Street takes 5h 21m and the fastest bus takes 5h. There is a bus service every few hours from Manchester to Harley Street. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Manchester and Harley Street. The earliest departure is at 2:50 AM at night, and the last departure from Manchester is at 11:59 PM which arrives into Harley Street at 6:30 AM. All services require a transfer at London Victoria and take an average of 5h 21m. The schedules shown below are for the next available departures.

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5h 4m • 1 changeWant to know about travelling from Manchester to Harley Street? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manchester to Harley Street. However, there are services departing from Manchester, Shudehill Interchange station and arriving at London Victoria station via London Victoria station. The journey, including transfers, takes approximately 5h 21m.
Manchester to Harley Street bus services, operated by FlixBus, depart from Manchester, Shudehill Interchange station.
Manchester to Harley Street bus services, operated by FlixBus, arrive at London Victoria station.
Book your Manchester to Harley Street bus tickets online with Omio.
The distance between Manchester and Harley Street is 259.8 km. The road distance is 294 km.
FlixBus operates a bus from Manchester, Shudehill Interchange to London Victoria hourly. Tickets cost £23–35 and the journey takes 4h 40m.