The average bus between Manchester and London Paddington takes 4h 54m and the fastest bus takes 4h 40m. The bus service runs several times per day from Manchester to London Paddington. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Manchester and London Paddington. The earliest departure is at 2:50 AM at night, and the last departure from Manchester is at 5:40 PM which arrives into London Paddington at 10:36 PM. All services require a transfer at London, Finchley Road ("Subway" restaurant) and take an average of 4h 54m. The schedules shown below are for the next available departures.

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4h 40m • 1 changeWant to know about travelling from Manchester to London Paddington? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manchester to London Paddington. However, there are services departing from Manchester station and arriving at London Paddington station via London, Finchley Road ("Subway" restaurant). The journey, including transfers, takes approximately 4h 54m.
Manchester to London Paddington bus services, operated by FlixBus, depart from Manchester, Shudehill Interchange station.
Manchester to London Paddington bus services, operated by FlixBus, arrive at London, Finchley Road ("Subway" restaurant) station.
Book your Manchester to London Paddington bus tickets online with FlixBus and National Express.
The distance between Manchester and London Paddington is 259.1 km. The road distance is 313 km.
FlixBus operates a bus from Manchester, Shudehill Interchange to London, Finchley Road ("Subway" restaurant) hourly. Tickets cost £19–35 and the journey takes 4h 5m.