Bus Manchester to London Paddington Station from £42 | Tickets & Timetables

Manchester to London Paddington Station buses

Travel from

Search accommodation with Expedia

Trip Overview

The average bus between Manchester and London Paddington Station takes 5h and the fastest bus takes 4h 40m. The bus service runs several times per day from Manchester to London Paddington Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h
Duration: 188 mi
Distance: £42
Average price: 5 times a day
Frequency

Bus

best

Take the bus from Manchester Central Coach Station to Finchley Road Stationbus 540 / ...

4h 33m

£36–85

Manchester to London Paddington Station bus times

Buses run 5 times a day between Manchester and London Paddington Station. The earliest departure is at 5:45 AM in the morning, and the last departure from Manchester is at 4:55 PM which arrives into London Paddington Station at 9:36 PM. All services require a transfer, and take on average 5h. The schedules shown below are for the next available departures.

Departing Sunday, August 16, 2026

6:05 AM → 10:51 AM
4h 46m • 1 change
8:55 AM → 2:51 PM
5h 56m • 1 change
10:55 AM → 3:51 PM
4h 56m • 1 change
1:25 PM → 6:10 PM
4h 45m • 1 change
Show more

Departing Monday, August 17, 2026

9:00 AM → 1:51 PM
4h 51m • 1 change
11:30 AM → 4:10 PM
4h 40m • 1 change
2:40 PM → 7:31 PM
4h 51m • 1 change
4:55 PM → 9:36 PM
4h 41m • 1 change

Departing Tuesday, August 18, 2026

9:00 AM → 1:51 PM
4h 51m • 1 change
11:30 AM → 4:10 PM
4h 40m • 1 change
2:40 PM → 7:31 PM
4h 51m • 1 change
4:55 PM → 9:36 PM
4h 41m • 1 change

Departing Wednesday, August 19, 2026

9:00 AM → 1:51 PM
4h 51m • 1 change
11:30 AM → 4:10 PM
4h 40m • 1 change
2:40 PM → 7:31 PM
4h 51m • 1 change
4:55 PM → 9:36 PM
4h 41m • 1 change

Departing Thursday, August 20, 2026

9:00 AM → 1:51 PM
4h 51m • 1 change
11:30 AM → 4:10 PM
4h 40m • 1 change
2:40 PM → 7:31 PM
4h 51m • 1 change
4:55 PM → 9:36 PM
4h 41m • 1 change

Departing Friday, August 21, 2026

5:45 AM → 10:51 AM
5h 6m • 1 change
8:50 AM → 2:51 PM
6h 1m • 1 change
10:55 AM → 3:51 PM
4h 56m • 1 change
1:10 PM → 6:10 PM
5h • 1 change
Show more

Departing Saturday, August 22, 2026

6:05 AM → 10:51 AM
4h 46m • 1 change
8:55 AM → 2:51 PM
5h 56m • 1 change
10:55 AM → 3:51 PM
4h 56m • 1 change
1:25 PM → 6:10 PM
4h 45m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Manchester to London Paddington Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.