The average bus between Manchester and Milton Keynes Central Station takes 4h and the fastest bus takes 3h 15m. There is a bus service every few hours from Manchester to Milton Keynes Central Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Manchester and Milton Keynes Central Station. The earliest departure is at 2:45 AM at night, and the last departure from Manchester is at 11:40 PM which arrives into Milton Keynes Central Station at 6:55 AM. All services require a transfer, and take on average 4h. The schedules shown below are for the next available departures.

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Want to know about travelling from Manchester to Milton Keynes Central Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manchester to Milton Keynes Central Station. However, there are services departing from Manchester station and arriving at Milton Keynes Central Station station via Milton Keynes Coachway. The journey, including transfers, takes approximately 4h.
Manchester to Milton Keynes Central Station bus services, operated by National Express, depart from Manchester Central Coach Station.
Manchester to Milton Keynes Central Station bus services, operated by National Express, arrive at Milton Keynes Coachway station.
The distance between Manchester and Milton Keynes Central Station is 188.6 km. The road distance is 250 km.
National Express operates a bus from Manchester Central Coach Station to Milton Keynes Coachway every 30 minutes. Tickets cost £29–70 and the journey takes 4h.