The average bus between Manchester and Piccadilly Circus (Station) takes 5h 26m and the fastest bus takes 4h 19m. There is a bus service every few hours from Manchester to Piccadilly Circus (Station). The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Manchester and Piccadilly Circus (Station). The earliest departure is at 2:45 AM at night, and the last departure from Manchester is at 7:30 PM which arrives into Piccadilly Circus (Station) at 11:49 PM. All services require a transfer at Finchley Road / O2 Centre and take an average of 5h 26m. The schedules shown below are for the next available departures.

5h 50m • 1 change

4h 43m • 1 change

5h 28m • 1 change

4h 50m • 1 change

5h 42m • 1 change

4h 52m • 1 change

5h 25m • 1 change

4h 48m • 1 change

5h 58m • 1 change

5h 9m • 1 change

6h 4m • 1 change

5h 10m • 1 change
Want to know about travelling from Manchester to Piccadilly Circus (Station)? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manchester to Piccadilly Circus (Station). However, there are services departing from Manchester station and arriving at Piccadilly Circus (Station) station via Finchley Road / O2 Centre. The journey, including transfers, takes approximately 5h 26m.
Manchester to Piccadilly Circus (Station) bus services, operated by National Express, depart from Shudehill Interchange station.
Manchester to Piccadilly Circus (Station) bus services, operated by National Express, arrive at Finchley Road / O2 Centre station.
The distance between Manchester and Piccadilly Circus (Station) is 261.2 km. The road distance is 325 km.
FlixBus operates a bus from Shudehill Interchange to Finchley Road / O2 Centre hourly. Tickets cost £23–40 and the journey takes 4h 35m.