The average bus between Manchester and Southwark Station takes 5h 54m and the fastest bus takes 4h 40m. There is a bus service every few hours from Manchester to Southwark Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Manchester and Southwark Station. The earliest departure is at 2:45 AM at night, and the last departure from Manchester is at 11:55 PM which arrives into Southwark Station at 7:15 AM. All services require a transfer at London, Finchley Road ("Subway" restaurant) and take an average of 5h 54m. The schedules shown below are for the next available departures.

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6h 16m • 1 changeWant to know about travelling from Manchester to Southwark Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manchester to Southwark Station. However, there are services departing from Manchester, Shudehill Interchange station and arriving at London, Finchley Road ("Subway" restaurant) station via London, Finchley Road ("Subway" restaurant) station. The journey, including transfers, takes approximately 5h 54m.
Manchester to Southwark Station bus services, operated by FlixBus, depart from Manchester, Shudehill Interchange station.
Manchester to Southwark Station bus services, operated by FlixBus, arrive at London, Finchley Road ("Subway" restaurant) station.
Book your Manchester to Southwark Station bus tickets online with Omio.
The distance between Manchester and Southwark Station is 262.9 km. The road distance is 298 km.
FlixBus operates a bus from Manchester, Shudehill Interchange to London, Finchley Road ("Subway" restaurant) every 3 hours. Tickets cost £23–35 and the journey takes 4h 5m.