The average bus between Manchester and Spitalfields takes 6h and the fastest bus takes 5h 27m. The bus service runs several times per day from Manchester to Spitalfields. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Manchester and Spitalfields. The earliest departure is at 2:50 AM at night, and the last departure from Manchester is at 11:59 PM which arrives into Spitalfields at 7:05 AM. All services require a transfer at Finchley Road / O2 Centre and take an average of 6h. The schedules shown below are for the next available departures.

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5h 50m • 1 changeWant to know about travelling from Manchester to Spitalfields? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manchester to Spitalfields. However, there are services departing from Manchester station and arriving at Spitalfields station via Finchley Road / O2 Centre. The journey, including transfers, takes approximately 6h.
Manchester to Spitalfields bus services, operated by FlixBus, depart from Shudehill Interchange station.
Manchester to Spitalfields bus services, operated by FlixBus, arrive at Finchley Road / O2 Centre station.
Book your Manchester to Spitalfields bus tickets online with FlixBus and National Express.
The distance between Manchester and Spitalfields is 262.6 km. The road distance is 327 km.
FlixBus operates a bus from Shudehill Interchange to Finchley Road / O2 Centre every 4 hours. Tickets cost £20–35 and the journey takes 4h 35m.