The average bus between Manchester and St Pancras takes 5h 29m and the fastest bus takes 4h 28m. There is a bus service every few hours from Manchester to St Pancras. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Manchester and St Pancras. The earliest departure is at 2:45 AM at night, and the last departure from Manchester is at 7:30 PM which arrives into St Pancras at 12:00 AM. All services require a transfer at Marble Arch and take an average of 5h 29m. The schedules shown below are for the next available departures.

5h 51m • 1 change
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4h 53m • 1 changeWant to know about travelling from Manchester to St Pancras? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manchester to St Pancras. However, there are services departing from Manchester Central Coach Station and arriving at Marble Arch station via Marble Arch station. The journey, including transfers, takes approximately 5h 29m.
Manchester to St Pancras bus services, operated by National Express, depart from Manchester Central Coach Station.
Manchester to St Pancras bus services, operated by National Express, arrive at Marble Arch station.
The distance between Manchester and St Pancras is 260 km. The road distance is 295 km.
National Express operates a bus from Manchester Central Coach Station to Marble Arch hourly. Tickets cost £30–55 and the journey takes 5h 40m.