The average bus between Manchester and Stoke Mandeville takes 6h 2m and the fastest bus takes 4h 55m. The bus service runs several times per day from Manchester to Stoke Mandeville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Manchester and Stoke Mandeville. The earliest departure is at 2:45 AM at night, and the last departure from Manchester is at 11:40 PM which arrives into Stoke Mandeville at 7:41 AM. All services require a transfer at Milton Keynes Coachway and take an average of 6h 2m. The schedules shown below are for the next available departures.



6h 31m • 3 changes


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5h 41m • 3 changes


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5h 16m • 3 changes


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5h 1m • 3 changes


5h 56m • 3 changes


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6h 36m • 3 changes


5h 21m • 3 changesWant to know about travelling from Manchester to Stoke Mandeville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manchester to Stoke Mandeville. However, there are services departing from Manchester station and arriving at Stoke Mandeville station via Milton Keynes Coachway. The journey, including transfers, takes approximately 6h 2m.
Manchester to Stoke Mandeville bus services, operated by National Express, depart from Manchester Central Coach Station.
Manchester to Stoke Mandeville bus services, operated by National Express, arrive at Milton Keynes Coachway station.
The distance between Manchester and Stoke Mandeville is 212.5 km. The road distance is 287 km.
National Express operates a bus from Manchester Central Coach Station to Milton Keynes Coachway hourly. Tickets cost £29–70 and the journey takes 4h.