Rome2Rio

Manhattan to Florence buses

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Trip Overview

The average bus between Manhattan and Florence takes 15h 7m and the fastest bus takes 15h. There is at least one bus per day from Manhattan to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

15h 7m
Duration
684 mi
Distance
$120
Average price
Once daily
Frequency

Manhattan to Florence bus times

Buses run once daily between Manhattan and Florence. The earliest departure is at 6:27 PM in the evening, and the last departure from Manhattan is at 6:40 PM which arrives into Florence at 9:40 AM. All services require a transfer at Broadway/West Houston St and take an average of 15h 7m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

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    Arrives next day

    MTA Bus CompanyFlixbus USAGreyhound USA15h 8m • 2 changes

Departing Friday, November 13, 2026

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    Arrives next day

    MTA Bus CompanyFlixbus USAGreyhound USA15h 8m • 2 changes

Departing Saturday, November 14, 2026

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    Arrives next day

    MTA Bus CompanyFlixbus USAGreyhound USA15h 13m • 2 changes

Departing Sunday, November 15, 2026

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    Arrives next day

    MTA Bus CompanyFlixbus USAGreyhound USA15h • 2 changes

Departing Monday, November 16, 2026

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    Arrives next day

    MTA Bus CompanyFlixbus USAGreyhound USA15h 8m • 2 changes

Departing Tuesday, November 17, 2026

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    Arrives next day

    MTA Bus CompanyFlixbus USAGreyhound USA15h 8m • 2 changes

Frequently asked questions

Want to know about travelling from Manhattan to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Manhattan to Florence.ExpandLaunch map view
  • Distance: 684.3 mi
  • Duration: 15h 7m

What companies run services between Manhattan, NY, USA and Florence, SC, USA?

Wanda Coach operates a bus from New York, NY to Florence, SC 3 times a day. Tickets cost $85–130 and the journey takes 12h.

Operators