The average bus between Manhattan and Hyannis takes 7h 31m and the fastest bus takes 6h 35m. There is a bus service every few hours from Manhattan to Hyannis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Manhattan and Hyannis. The earliest departure is at 7:00 AM in the morning, and the last departure from Manhattan is at 11:30 PM which arrives into Hyannis at 8:15 AM. All services require a transfer at Boston and take an average of 7h 31m. The schedules shown below are for the next available departures.

7h 15m • 1 change

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7h 35m • 1 change

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6h 45m • 1 change

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6h 45m • 1 change

7h 15m • 1 change

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6h 45m • 1 change

7h 15m • 1 change

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6h 45m • 1 change

6h 45m • 1 change

7h 15m • 1 change
Want to know about travelling from Manhattan to Hyannis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manhattan to Hyannis. However, there are services departing from Manhattan station and arriving at Hyannis station via Boston. The journey, including transfers, takes approximately 7h 31m.
Manhattan to Hyannis bus services, operated by Peter Pan Bus Lines, depart from New York station.
Manhattan to Hyannis bus services, operated by Peter Pan Bus Lines, arrive at Hyannis Transportation Center station.
Book your Manhattan to Hyannis bus tickets online with Peter Pan Bus Lines and Plymouth & Brockton.
The distance between Manhattan and Hyannis is 322.9 km. The road distance is 460 km.
You can take a bus from New York to Hyannis Transportation Center via Boston and Boston South Buses in around 7h 7m.