The average bus between Manhattan and Middletown takes 4h 39m and the fastest bus takes 3h 27m. The bus service runs several times per day from Manhattan to Middletown. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Manhattan and Middletown. The earliest departure is at 4:30 AM at night, and the last departure from Manhattan is at 9:30 PM which arrives into Middletown at 6:40 AM. All services require a transfer at Hartford and take an average of 4h 39m. The schedules shown below are for the next available departures.

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3h 57m • 1 change
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3h 57m • 1 change
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4h 27m • 1 changeWant to know about travelling from Manhattan to Middletown? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manhattan to Middletown. However, there are services departing from New York station and arriving at Main St @ opp Ferry St station via Hartford station. The journey, including transfers, takes approximately 4h 39m.
Manhattan to Middletown bus services, operated by Peter Pan Bus Lines, depart from New York station.
Manhattan to Middletown bus services, operated by CT Transit, arrive at Main St @ opp Ferry St station.
The distance between Manhattan and Middletown is 140.1 km. The road distance is 154 km.
You can take a bus from New York to Main St @ opp Ferry St via Hartford and Main St @ Gold St in around 4h 31m.