The average bus between Manhattan and San Antonio takes 2d and the fastest bus takes 44h 5m. The bus service runs several times per day from Manhattan to San Antonio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Manhattan and San Antonio. The earliest departure is at 2:30 AM at night, and the last departure from Manhattan is at 11:00 PM which arrives into San Antonio at 6:05 PM. All services require a transfer at Centre St/Grand St and take an average of 2d. The schedules shown below are for the next available departures.
Arrives +2 days


47h 50m • 2 changes
Arrives +2 days


43h 5m • 2 changes
Arrives +2 days


2d 2h • 2 changes
Arrives +2 days


47h 50m • 2 changes
Arrives +2 days


43h 5m • 2 changes
Arrives +2 days


2d 2h • 2 changes
Arrives +2 days


47h 50m • 2 changes
Arrives +2 days


43h 5m • 2 changes
Want to know about travelling from Manhattan to San Antonio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manhattan to San Antonio. However, there are services departing from Manhattan station and arriving at San Antonio station via Memphis - Summer Ave. The journey, including transfers, takes approximately 2d.
Manhattan to San Antonio bus services, operated by Greyhound USA, depart from New York station.
Manhattan to San Antonio bus services, operated by Greyhound USA, arrive at Tornado Bus Co - San Antonio station.
Book your Manhattan to San Antonio bus tickets online with Greyhound USA.
The distance between Manhattan and San Antonio is 2,551.1 km. The road distance is 3,039 km.
You can take a bus from 5 Av/E 79 St to S. St. Mary's & Nueva via Centre St/Grand St, New York, Memphis - Summer Ave, Tornado Bus Co - West Memphis, Tornado Bus Co - San Antonio, and I-35 S Access & Yarrow Blvd in around 36h 49m.