The average bus between Manhattan and South Station takes 4h 55m and the fastest bus takes 4h 15m. There is an hourly bus service from Manhattan to South Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Manhattan and South Station. The earliest departure is at 1:00 AM at night, and the last departure from Manhattan is at 11:59 PM which arrives into South Station at 4:40 AM. All services run direct with no transfers required, and take on average 4h 55m. The schedules shown below are for the next available departures.
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Want to know about travelling from Manhattan to South Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Manhattan station and arriving at South Station station. Services depart hourly, and operate 3 times a day. The journey takes approximately 4h 55m.
Manhattan to South Station bus services, operated by Greyhound USA, depart from New York Midtown station.
Manhattan to South Station bus services, operated by Greyhound USA, arrive at Boston station.
Book your Manhattan to South Station bus tickets online with Greyhound USA and Flixbus USA.
The distance between Manhattan and South Station is 298.4 km. The road distance is 342 km.
Flixbus USA operates a bus from New York Midtown to Boston hourly. Tickets cost $30–55 and the journey takes 4h 20m. Two other operators also service this route.