Bus Mannheim to Neu-Isenburg | Tickets & Timetables

Mannheim to Neu-Isenburg buses

Travel from

Search accommodation with Expedia

Trip Overview

The average bus between Mannheim and Neu-Isenburg takes 1h 34m and the fastest bus takes 1h 22m. The bus service runs several times per day from Mannheim to Neu-Isenburg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

1h 34m
Duration: 89 km
Distance: Every 2 hours
Frequency

Bus

best

Take the bus from Mannheim central bus station to Frankfurt Airportbus FlixBus 108 / ...
Take the bus from Frankfurt to Neu-Isenburg Isenburgzentrum Südbus X19

1h 31m

Mannheim to Neu-Isenburg bus times

Buses run every 2 hours between Mannheim and Neu-Isenburg. The earliest departure is at 12:04 AM at night, and the last departure from Mannheim is at 4:15 PM which arrives into Neu-Isenburg at 5:52 PM. All services require a transfer at Frankfurt Airport and take an average of 1h 34m. The schedules shown below are for the next available departures.

Departing Monday, August 10, 2026

10:55 AM → 2:22 PM
3h 27m • 1 change
11:25 AM → 1:08 PM
1h 43m • 1 change
2:25 PM → 6:08 PM
3h 43m • 1 change
3:40 PM → 5:22 PM
1h 42m • 1 change
Show more

Departing Tuesday, August 11, 2026

12:04 AM → 1:33 AM
1h 29m • 1 change
2:30 AM → 6:07 AM
3h 37m • 1 change
2:40 AM → 4:03 AM
1h 23m • 1 change
5:00 AM → 6:22 AM
1h 22m • 1 change
Show more

Departing Wednesday, August 12, 2026

12:04 AM → 1:33 AM
1h 29m • 1 change
2:30 AM → 6:07 AM
3h 37m • 1 change
2:40 AM → 4:03 AM
1h 23m • 1 change
5:00 AM → 6:22 AM
1h 22m • 1 change
Show more

Departing Thursday, August 13, 2026

12:04 AM → 1:33 AM
1h 29m • 1 change
2:30 AM → 6:07 AM
3h 37m • 1 change
2:40 AM → 4:03 AM
1h 23m • 1 change
5:00 AM → 6:22 AM
1h 22m • 1 change
Show more

Departing Friday, August 14, 2026

12:04 AM → 1:33 AM
1h 29m • 1 change
2:30 AM → 6:07 AM
3h 37m • 1 change
2:40 AM → 4:03 AM
1h 23m • 1 change
5:00 AM → 6:22 AM
1h 22m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Mannheim to Neu-Isenburg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.