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Mannheim to Palermo buses

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Trip Overview

The bus between Mannheim and Palermo takes 44h 15m. The bus runs, on average, 5 times per week from Mannheim to Palermo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

44h 15m
Duration
2,250 km
Distance
€242
Average price
5 times a week
Frequency

Mannheim to Palermo bus times

Buses run 5 times a week between Mannheim and Palermo. The service departs Mannheim at 7:00 PM in the evening, which arrives into Palermo at 15:15:00. All services require a transfer, and take on average 44h 15m. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBus44h 15m • 1 change

Departing Tuesday, November 3, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBus44h 15m • 1 change

Departing Wednesday, November 4, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBus44h 15m • 1 change

Departing Thursday, November 5, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBus44h 15m • 1 change

Departing Friday, November 6, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBus44h 15m • 1 change

Frequently asked questions

Want to know about travelling from Mannheim to Palermo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mannheim to Palermo.ExpandLaunch map view
  • Distance: 2,249.9 km
  • Duration: 44h 15m

What companies run services between Mannheim, Germany and Palermo, Italy?

You can take a bus from Mannheim central bus station to Palermo via Roma, Autostazione Tiburtina in around 33h 45m.

Operators