The average bus between Massachusetts and Des Moines takes 45h 10m and the fastest bus takes 41h 15m. There is at least one bus per day from Massachusetts to Des Moines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Massachusetts and Des Moines. The earliest departure is at 1:00 AM at night, and the last departure from Massachusetts is at 3:00 PM which arrives into Des Moines at 2:35 PM. All services require a transfer at New York Midtown and take an average of 45h 10m. The schedules shown below are for the next available departures.
Want to know about travelling from Massachusetts to Des Moines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Massachusetts to Des Moines. However, there are services departing from Massachusetts station and arriving at Des Moines station via New York Midtown. The journey, including transfers, takes approximately 45h 10m.
Massachusetts to Des Moines bus services, operated by Flixbus USA, depart from Boston station.
Massachusetts to Des Moines bus services, operated by Flixbus USA, arrive at Des Moines station.
Book your Massachusetts to Des Moines bus tickets online with Flixbus USA and Greyhound USA.
The distance between Massachusetts and Des Moines is 1,780.6 km. The road distance is 2,477 km.
You can take a bus from Boston to Des Moines via New York Midtown and Chicago Bus Station in around 33h 15m.
