The average bus between Massachusetts and Illinois takes 25h 38m and the fastest bus takes 21h 10m. The bus service runs several times per day from Massachusetts to Illinois. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Massachusetts and Illinois. The earliest departure is at 1:30 AM at night, and the last departure from Massachusetts is at 5:15 PM which arrives into Illinois at 1:25 PM. All services require a transfer, and take on average 25h 38m. The schedules shown below are for the next available departures.
Arrives next day

28h 40m • 1 change
Arrives next day

20h 10m • 1 change
Arrives next day

24h 10m • 1 change
Arrives next day

20h 10m • 1 change
Arrives next day

28h 40m • 1 change
Arrives next day

20h 10m • 1 change
Arrives next day

28h 40m • 1 change
Arrives next day

20h 10m • 1 change
Want to know about travelling from Massachusetts to Illinois? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Massachusetts to Illinois. However, there are services departing from Massachusetts station and arriving at Illinois station via Newark Penn Station station. The journey, including transfers, takes approximately 25h 38m.
Massachusetts to Illinois bus services, operated by Greyhound USA, depart from Boston station.
Massachusetts to Illinois bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Book your Massachusetts to Illinois bus tickets online with Greyhound USA and Flixbus USA.
The distance between Massachusetts and Illinois is 1,474.8 km. The road distance is 1,760 km.
You can take a bus from Boston to Chicago Bus Station via Newark Penn Station in around 22h 40m.