The average bus between Massachusetts and Mississippi takes 37h and the fastest bus takes 34h 50m. The bus service runs several times per day from Massachusetts to Mississippi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Massachusetts and Mississippi. The earliest departure is at 2:30 AM at night, and the last departure from Massachusetts is at 5:30 PM which arrives into Mississippi at 7:15 AM. All services require a transfer at New York Midtown and take an average of 37h. The schedules shown below are for the next available departures.
Arrives next day


33h 50m • 2 changes
Arrives +2 days


37h 45m • 2 changes
Arrives next day


33h 50m • 2 changes
Arrives +2 days


37h 45m • 2 changes
Arrives next day


33h 50m • 2 changes
Arrives +2 days


37h 45m • 2 changes
Want to know about travelling from Massachusetts to Mississippi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Massachusetts to Mississippi. However, there are services departing from Massachusetts station and arriving at Mississippi station via New York Midtown. The journey, including transfers, takes approximately 37h.
Massachusetts to Mississippi bus services, operated by Flixbus USA, depart from Boston station.
Massachusetts to Mississippi bus services, operated by Flixbus USA, arrive at Jackson station.
Book your Massachusetts to Mississippi bus tickets online with Flixbus USA and Greyhound USA.
The distance between Massachusetts and Mississippi is 1,870.6 km. The road distance is 2,484 km.
You can take a bus from Boston to Jackson via New York Midtown and Atlanta Bus Station in around 32h 5m.