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Mayo Clinic to Ann Arbor buses

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Trip Overview

The bus between Mayo Clinic and Ann Arbor takes 30h 50m. The bus runs, on average, 3 times per week from Mayo Clinic to Ann Arbor. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

30h 50m
Duration
610 mi
Distance
$144
Average price
3 times a week
Frequency

Mayo Clinic to Ann Arbor bus times

Buses run 3 times a week between Mayo Clinic and Ann Arbor. The service departs Mayo Clinic at 12:35 PM in the afternoon, which arrives into Ann Arbor at 19:25:00. All services require a transfer at Rochester and take an average of 30h 50m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

  •  → 

    Arrives next day

    Jefferson LinesFlixbus USA30h 50m • 1 change

Departing Saturday, November 7, 2026

  •  → 

    Arrives next day

    Jefferson LinesFlixbus USA30h 50m • 1 change

Departing Sunday, November 8, 2026

  •  → 

    Arrives next day

    Jefferson LinesFlixbus USA30h 50m • 1 change

Frequently asked questions

Want to know about travelling from Mayo Clinic to Ann Arbor? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mayo Clinic to Ann Arbor.ExpandLaunch map view
  • Distance: 610 mi
  • Duration: 30h 50m

What companies run services between Mayo Clinic, MN, USA and Ann Arbor, MI, USA?

You can take a vehicle from Mayo Clinic to Ann Arbor via Rochester, Milwaukee, and Milwaukee Intermodal Station in around 13h 26m.

Operators