The bus between Mayo Clinic and Chicago takes 8h 45m. There is at least one bus per day from Mayo Clinic to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Mayo Clinic and Chicago. The earliest departure is at 12:35 PM in the afternoon, and the last departure from Mayo Clinic is at 12:35 PM which arrives into Chicago at 8:20 PM. All services require a transfer at Rochester and take an average of 8h 45m. The schedules shown below are for the next available departures.
Want to know about travelling from Mayo Clinic to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mayo Clinic to Chicago. However, there are services departing from Mayo Clinic station and arriving at Chicago station via Madison. The journey, including transfers, takes approximately 8h 45m.
Mayo Clinic to Chicago bus services, operated by Jefferson Lines, depart from Rochester station.
Mayo Clinic to Chicago bus services, operated by Jefferson Lines, arrive at W Jackson Blvd, after S Clinton St station.
The distance between Mayo Clinic and Chicago is 460.4 km. The road distance is 576 km.
You can take a vehicle from Mayo Clinic to W Jackson Blvd, after S Clinton St via Rochester, Madison, and 250 N. Lake St - Madison UW Campus in around 9h 1m.
