The average bus between Mayo Clinic and Nashville takes 24h 35m and the fastest bus takes 22h 10m. The bus service runs several times per day from Mayo Clinic to Nashville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Mayo Clinic and Nashville. The earliest departure is at 12:35 PM in the afternoon, and the last departure from Mayo Clinic is at 1:05 PM which arrives into Nashville at 4:05 PM. All services require a transfer at Rochester, MN and take an average of 24h 35m. The schedules shown below are for the next available departures.
Arrives next day


21h 10m • 2 changes
Arrives next day


27h • 2 changes
Arrives next day


21h 10m • 2 changes
Arrives next day


27h • 2 changes
Arrives next day


21h 10m • 2 changes
Arrives next day


27h • 2 changes
Want to know about travelling from Mayo Clinic to Nashville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mayo Clinic to Nashville. However, there are services departing from Mayo Clinic station and arriving at Nashville station via UW-Madison. The journey, including transfers, takes approximately 24h 35m.
Mayo Clinic to Nashville bus services, operated by Jefferson Lines, depart from Rochester, MN station.
Mayo Clinic to Nashville bus services, operated by Jefferson Lines, arrive at Nashville Bus Station.
The distance between Mayo Clinic and Nashville is 997.8 km. The road distance is 1,368 km.
You can take a vehicle from Mayo Clinic to Nashville Bus Station via Rochester, MN, 250 N. Lake St - Madison UW Campus, W Jackson Blvd, after S Clinton St, and Chicago Bus Station in around 20h 18m.