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Mayo Clinic to New York buses

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Trip Overview

The average bus between Mayo Clinic and New York takes 43h 34m and the fastest bus takes 41h 55m. The bus runs, on average, 6 times per week from Mayo Clinic to New York. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

43h 34m
Duration
1,357 mi
Distance
$293
Average price
6 times a week
Frequency

Mayo Clinic to New York bus times

Buses run 6 times a week between Mayo Clinic and New York. The service departs Mayo Clinic at 12:35 PM in the afternoon, which arrives into New York at 06:30:00. All services require a transfer at Rochester and take an average of 43h 34m. The schedules shown below are for the next available departures.

Departing Sunday, October 25, 2026

  •  → 

    Arrives +2 days

    Jefferson LinesFlixbus USAFlixbus USA41h 55m • 2 changes

Departing Monday, October 26, 2026

  •  → 

    Arrives +2 days

    Jefferson LinesFlixbus USAFlixbus USA41h 55m • 2 changes

Departing Tuesday, October 27, 2026

  •  → 

    Arrives +2 days

    Jefferson LinesFlixbus USAFlixbus USA2d 3h • 2 changes

Departing Wednesday, October 28, 2026

  •  → 

    Arrives +2 days

    Jefferson LinesFlixbus USAFlixbus USA41h 55m • 2 changes

Departing Thursday, October 29, 2026

  •  → 

    Arrives +2 days

    Jefferson LinesFlixbus USAFlixbus USA41h 55m • 2 changes

Departing Friday, October 30, 2026

  •  → 

    Arrives +2 days

    Jefferson LinesFlixbus USAFlixbus USA41h 55m • 2 changes

Frequently asked questions

Want to know about travelling from Mayo Clinic to New York? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mayo Clinic to New York.ExpandLaunch map view
  • Distance: 1,357 mi
  • Duration: 43h 34m

What companies run services between Mayo Clinic, MN, USA and New York, NY, USA?

You can take a vehicle from Mayo Clinic to New York Midtown via Rochester, Milwaukee, Milwaukee Intermodal Station, and Chicago Bus Station in around 29h 38m.

Operators