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Mayo Clinic to Port Huron buses

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Trip Overview

The bus between Mayo Clinic and Port Huron takes 34h 56m. The bus runs, on average, once a week from Mayo Clinic to Port Huron. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

34h 56m
Duration
707 mi
Distance
$220
Average price
Once a week
Frequency

Mayo Clinic to Port Huron bus times

Buses run once a week between Mayo Clinic and Port Huron. The service departs Mayo Clinic at 12:35 PM in the afternoon, which arrives into Port Huron at 23:31:00. All services require a transfer at Rochester and take an average of 34h 56m. The schedules shown below are for the next available departures.

Departing Saturday, October 10, 2026

  •  → 

    Arrives next day

    Jefferson LinesRockland CoachesAmtrak34h 56m • 2 changes

Frequently asked questions

Want to know about travelling from Mayo Clinic to Port Huron? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mayo Clinic to Port Huron.ExpandLaunch map view
  • Distance: 707.5 mi
  • Duration: 34h 56m

What companies run services between Mayo Clinic, MN, USA and Port Huron, MI, USA?

You can take a vehicle from Mayo Clinic to Port Huron Station via Rochester, Madison, 250 N. Lake St - Madison UW Campus, W Jackson Blvd, after S Clinton St, and Chicago Union Station in around 16h 30m.

Operators