The average bus between Mayo Clinic and St. Louis takes 20h 18m and the fastest bus takes 18h 45m. The bus runs, on average, 6 times per week from Mayo Clinic to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between Mayo Clinic and St. Louis. The earliest departure is at 12:35 PM in the afternoon, and the last departure from Mayo Clinic is at 12:35 PM which arrives into St. Louis at 6:20 AM. All services require a transfer at Rochester and take an average of 20h 18m. The schedules shown below are for the next available departures.
Want to know about travelling from Mayo Clinic to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mayo Clinic to St. Louis. However, there are services departing from Mayo Clinic station and arriving at St. Louis station via Milwaukee. The journey, including transfers, takes approximately 20h 18m.
Mayo Clinic to St. Louis bus services, operated by Jefferson Lines, depart from Rochester station.
Mayo Clinic to St. Louis bus services, operated by Jefferson Lines, arrive at St Louis Bus Station.
The distance between Mayo Clinic and St. Louis is 629 km. The road distance is 1,101 km.
You can take a vehicle from Mayo Clinic to St Louis Bus Station via Rochester, Milwaukee, Milwaukee Intermodal Station, and Chicago Bus Station in around 15h 23m.
