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Mechanicsburg to Cleveland buses

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Trip Overview

The average bus between Mechanicsburg and Cleveland takes 25h 28m and the fastest bus takes 15h. The bus runs, on average, 5 times per week from Mechanicsburg to Cleveland. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

25h 28m
Duration
356 mi
Distance
$64
Average price
5 times a week
Frequency

Mechanicsburg to Cleveland bus times

Buses run 5 times a week between Mechanicsburg and Cleveland. The earliest departure is at 12:18 PM in the afternoon, and the last departure from Mechanicsburg is at 4:48 PM which arrives into Cleveland at 7:19 AM. All services require a transfer at Market Square Transfer Center and take an average of 25h 28m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    Rabbit TransitFlixbus USAFlixbus USAMETRO RTA19h • 3 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    Rabbit TransitFlixbus USAFlixbus USAMETRO RTA15h • 3 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives +2 days

    Rabbit TransitFlixbus USAFlixbus USAMETRO RTA39h 50m • 3 changes
  •  → 

    Arrives +2 days

    Rabbit TransitFlixbus USAFlixbus USAMETRO RTA38h 30m • 3 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    Rabbit TransitFlixbus USAFlixbus USAMETRO RTA15h • 3 changes

Frequently asked questions

Want to know about travelling from Mechanicsburg to Cleveland? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mechanicsburg to Cleveland.ExpandLaunch map view
  • Distance: 355.8 mi
  • Duration: 25h 28m

What companies run services between Mechanicsburg, Cumberland County, PA, USA and Cleveland, OH, USA?

You can take a bus from E Main St & Arch St EB to W. Prospect Ave & Superior Ave via Market Square Transfer Center, Harrisburg Bus Station, State College Regional Airport, and RKP Transit Center in around 10h 26m.

Operators