The average bus between Mechanicsburg and St. Louis takes 20h 53m and the fastest bus takes 20h 6m. The bus service runs several times per day from Mechanicsburg to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Mechanicsburg and St. Louis. The earliest departure is at 12:19 PM in the afternoon, and the last departure from Mechanicsburg is at 7:19 PM which arrives into St. Louis at 3:10 PM. All services require a transfer at Market Square Transfer Center and take an average of 20h 53m. The schedules shown below are for the next available departures.
Want to know about travelling from Mechanicsburg to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mechanicsburg to St. Louis. However, there are services departing from Mechanicsburg station and arriving at St. Louis station via St Louis Bus Station station. The journey, including transfers, takes approximately 20h 53m.
Mechanicsburg to St. Louis bus services, operated by Rabbit Transit, depart from Harrisburg Bus Station.
Mechanicsburg to St. Louis bus services, operated by Rabbit Transit, arrive at St Louis Bus Station.
The distance between Mechanicsburg and St. Louis is 1,145.8 km. The road distance is 1,307 km.
Greyhound USA operates a bus from Harrisburg Bus Station to St Louis Bus Station twice daily. Tickets cost $130–210 and the journey takes 18h 5m.
