Rome2Rio

Medellín to Madrid buses

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Trip Overview

The average bus between Medellín and Madrid takes 6h 52m and the fastest bus takes 4h 40m. There is at least one bus per day from Medellín to Madrid. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 52m
Duration
320 km
Distance
€36
Average price
Once daily
Frequency

Medellín to Madrid bus times

Buses run once daily between Medellín and Madrid. The earliest departure is at 8:20 AM in the morning, and the last departure from Medellín is at 8:10 PM which arrives into Madrid at 1:00 PM. All services require a transfer, and take on average 6h 52m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

  •  → 

    InterbusAutocares Grupo Samar4h 40m • 1 change

Departing Wednesday, November 11, 2026

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    InterbusAutocares Grupo Samar4h 40m • 1 change

Departing Thursday, November 12, 2026

  •  → 

    InterbusAutocares Grupo Samar4h 40m • 1 change

Departing Friday, November 13, 2026

  •  → 

    InterbusAutocares Grupo Samar5h 25m • 1 change
  •  → 

    Arrives next day

    InterbusAutocares Grupo Samar16h 50m • 1 change

Departing Saturday, November 14, 2026

  •  → 

    InterbusAutocares Grupo Samar6h 25m • 1 change

Departing Monday, November 16, 2026

  •  → 

    InterbusAutocares Grupo Samar5h 25m • 1 change

Frequently asked questions

Want to know about travelling from Medellín to Madrid? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Medellín to Madrid.ExpandLaunch map view
  • Distance: 320.5 km
  • Duration: 6h 52m

What companies run services between Medellín, Spain and Madrid, Spain?

Autocares Grupo Samar operates a bus from Don Benito to Estación Sur de Autobuses twice daily. Tickets cost €30–45 and the journey takes 4h 15m.

Operators