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Melrose Park to Indianapolis buses

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Trip Overview

The average bus between Melrose Park and Indianapolis takes 5h 45m and the fastest bus takes 4h 56m. The bus service runs several times per day from Melrose Park to Indianapolis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 45m
Duration
194 mi
Distance
$50
Average price
5 times a day
Frequency

Bus via Kedzie-Homan (Greyhound)

best
  1. Take the bus from Chicago Bus Station to Indianapolis Union Stationbus bus Greyhound US0100 / ...
5h 29m
$37–60

Melrose Park to Indianapolis bus times

Buses run 5 times a day between Melrose Park and Indianapolis. The earliest departure is at 5:17 AM in the morning, and the last departure from Melrose Park is at 11:05 PM which arrives into Indianapolis at 11:50 AM. All services require a transfer at Forest Park CTA Station - Bus Stop A and take an average of 5h 45m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

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    Arrives next day

    Pace BusPace BusChicago Transit (CTA)Flixbus USA5h 31m • 3 changes

Departing Monday, November 9, 2026

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    Pace BusPace BusChicago Transit (CTA)Flixbus USA5h 33m • 3 changes

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    Pace BusPace BusChicago Transit (CTA)Flixbus USA5h 13m • 3 changes

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    Pace BusPace BusChicago Transit (CTA)Flixbus USA5h 13m • 3 changes

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    Pace BusPace BusChicago Transit (CTA)Flixbus USA5h 4m • 3 changes
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Departing Tuesday, November 10, 2026

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    Pace BusPace BusChicago Transit (CTA)Flixbus USA5h 33m • 3 changes

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    Pace BusPace BusChicago Transit (CTA)Flixbus USA5h 13m • 3 changes

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    Pace BusPace BusChicago Transit (CTA)Flixbus USA5h 13m • 3 changes

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    Pace BusPace BusChicago Transit (CTA)Flixbus USA5h 4m • 3 changes
  • Show more

Departing Wednesday, November 11, 2026

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    Pace BusPace BusChicago Transit (CTA)Flixbus USA5h 13m • 3 changes

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    Pace BusPace BusChicago Transit (CTA)Flixbus USA6h 19m • 3 changes

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    Arrives next day

    Pace BusPace BusChicago Transit (CTA)Flixbus USA5h 38m • 3 changes

Departing Thursday, November 12, 2026

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    Pace BusPace BusChicago Transit (CTA)Flixbus USA5h 13m • 3 changes

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    Pace BusPace BusChicago Transit (CTA)Flixbus USA5h 13m • 3 changes

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    Pace BusPace BusChicago Transit (CTA)Flixbus USA5h 4m • 3 changes

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    Pace BusPace BusChicago Transit (CTA)Flixbus USA6h 19m • 3 changes
  • Show more

Departing Friday, November 13, 2026

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    Pace BusPace BusChicago Transit (CTA)Flixbus USA5h 33m • 3 changes

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    Pace BusPace BusChicago Transit (CTA)Flixbus USA5h 13m • 3 changes

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    Pace BusPace BusChicago Transit (CTA)Flixbus USA5h 13m • 3 changes

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    Pace BusPace BusChicago Transit (CTA)Flixbus USA5h 4m • 3 changes
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Departing Saturday, November 14, 2026

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    Pace BusPace BusChicago Transit (CTA)Flixbus USA5h 44m • 3 changes

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    Pace BusPace BusChicago Transit (CTA)Flixbus USA5h 29m • 3 changes

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    Pace BusPace BusChicago Transit (CTA)Flixbus USA5h 39m • 3 changes

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    Pace BusPace BusChicago Transit (CTA)Flixbus USA6h 24m • 3 changes

Frequently asked questions

Want to know about travelling from Melrose Park to Indianapolis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Melrose Park to Indianapolis.ExpandLaunch map view
  • Distance: 194 mi
  • Duration: 5h 45m

What companies run services between Melrose Park, IL, USA and Indianapolis, IN, USA?

Greyhound USA operates a bus from Chicago Bus Station to Indianapolis Union Station 5 times a day. Tickets cost $30–50 and the journey takes 3h 5m.

Operators