Mesa to Palm Desert Buses

Mesa to Palm Desert buses

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Trip Overview

The average bus between Mesa and Palm Desert takes 9h 20m and the fastest bus takes 7h 34m. The bus service runs several times per day from Mesa to Palm Desert. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

9h 20m
Duration: 272 mi
Distance: $77
Average price: 3 times a day
Frequency

Bus

best

Take the bus from 2707 W McDowell Rd - Phoenix to Indio Bus Stationbus El Paso

7h 12m

$67–87

Mesa to Palm Desert bus times

Buses run 3 times a day between Mesa and Palm Desert. The earliest departure is at 5:02 AM in the morning, and the last departure from Mesa is at 10:04 PM which arrives into Palm Desert at 6:45 AM. All services require a transfer at Downtown Phx Hub/Washington St and take an average of 9h 20m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

6:21 AM → 1:19 PM
7h 58m • 3 changes
9:12 AM → 3:55 PM
7h 43m • 3 changes
11:12 AM → 8:13 PM
10h 1m • 3 changes
8:18 PM → 5:45 AM
Arrives next day
10h 27m • 3 changes
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Departing Monday, November 9, 2026

5:02 AM → 1:19 PM
9h 17m • 3 changes
9:04 PM → 5:45 AM
Arrives next day
9h 41m • 3 changes
10:04 PM → 6:45 AM
Arrives next day
9h 41m • 3 changes

Departing Tuesday, November 10, 2026

5:02 AM → 1:19 PM
9h 17m • 3 changes
9:04 PM → 5:45 AM
Arrives next day
9h 41m • 3 changes
10:04 PM → 6:45 AM
Arrives next day
9h 41m • 3 changes

Departing Wednesday, November 11, 2026

5:02 AM → 1:19 PM
9h 17m • 3 changes
9:04 PM → 5:45 AM
Arrives next day
9h 41m • 3 changes
10:04 PM → 6:45 AM
Arrives next day
9h 41m • 3 changes

Departing Thursday, November 12, 2026

5:02 AM → 1:19 PM
9h 17m • 3 changes
9:04 PM → 5:45 AM
Arrives next day
9h 41m • 3 changes
10:04 PM → 6:45 AM
Arrives next day
9h 41m • 3 changes

Departing Friday, November 13, 2026

5:02 AM → 1:19 PM
9h 17m • 3 changes
9:04 PM → 5:45 AM
Arrives next day
9h 41m • 3 changes
10:04 PM → 6:45 AM
Arrives next day
9h 41m • 3 changes

Departing Saturday, November 14, 2026

6:26 AM → 1:19 PM
7h 53m • 3 changes
9:21 AM → 3:55 PM
7h 34m • 3 changes
11:51 AM → 8:13 PM
9h 22m • 3 changes

Frequently asked questions

Want to know about travelling from Mesa to Palm Desert? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Trip Overview

Bus