Mesa to Palm Desert Buses

Mesa to Palm Desert buses

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Trip Overview

The average bus between Mesa and Palm Desert takes 9h 22m and the fastest bus takes 7h 31m. The bus service runs several times per day from Mesa to Palm Desert. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

9h 22m
Duration: 272 mi
Distance: $77
Average price: 3 times a day
Frequency

Bus

best

Take the bus from 2707 W McDowell Rd - Phoenix to Indio Bus Stationbus El Paso

7h 15m

$67–87

Mesa to Palm Desert bus times

Buses run 3 times a day between Mesa and Palm Desert. The earliest departure is at 5:02 AM in the morning, and the last departure from Mesa is at 10:29 PM which arrives into Palm Desert at 1:19 PM. All services require a transfer at Downtown Phx Hub/Washington St and take an average of 9h 22m. The schedules shown below are for the next available departures.

Departing Monday, October 19, 2026

5:02 AM → 1:19 PM
8h 17m • 3 changes
7:33 PM → 5:45 AM
Arrives next day
10h 12m • 3 changes
10:04 PM → 7:15 AM
Arrives next day
9h 11m • 3 changes

Departing Tuesday, October 20, 2026

5:02 AM → 1:19 PM
8h 17m • 3 changes
7:33 PM → 5:45 AM
Arrives next day
10h 12m • 3 changes
10:04 PM → 7:15 AM
Arrives next day
9h 11m • 3 changes

Departing Wednesday, October 21, 2026

5:02 AM → 1:19 PM
8h 17m • 3 changes
7:33 PM → 5:45 AM
Arrives next day
10h 12m • 3 changes
10:04 PM → 7:15 AM
Arrives next day
9h 11m • 3 changes

Departing Thursday, October 22, 2026

5:02 AM → 1:19 PM
8h 17m • 3 changes
7:33 PM → 5:45 AM
Arrives next day
10h 12m • 3 changes
10:04 PM → 7:15 AM
Arrives next day
9h 11m • 3 changes

Departing Friday, October 23, 2026

5:02 AM → 1:19 PM
8h 17m • 3 changes
7:33 PM → 5:45 AM
Arrives next day
10h 12m • 3 changes
10:04 PM → 7:15 AM
Arrives next day
9h 11m • 3 changes

Departing Saturday, October 24, 2026

5:27 AM → 1:19 PM
7h 52m • 3 changes
8:24 AM → 3:55 PM
7h 31m • 3 changes
10:51 AM → 8:13 PM
9h 22m • 3 changes
7:26 PM → 5:45 AM
Arrives next day
10h 19m • 3 changes
Show more

Departing Sunday, October 25, 2026

8:17 AM → 3:55 PM
7h 38m • 3 changes
10:12 AM → 8:13 PM
10h 1m • 3 changes

Frequently asked questions

Want to know about travelling from Mesa to Palm Desert? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Trip Overview

Bus