The average bus between Mesa and San Francisco takes 21h 21m and the fastest bus takes 21h 10m. The bus runs, on average, 5 times per week from Mesa to San Francisco. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a week between Mesa and San Francisco. The earliest departure is at 9:12 AM in the morning, and the last departure from Mesa is at 10:00 AM which arrives into San Francisco at 7:10 AM. All services require a transfer at University Dr & Rural Rd and take an average of 21h 21m. The schedules shown below are for the next available departures.
Want to know about travelling from Mesa to San Francisco? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mesa to San Francisco. However, there are services departing from Mesa station and arriving at San Francisco station via Los Angeles Union Station station. The journey, including transfers, takes approximately 21h 21m.
Mesa to San Francisco bus services, operated by Valley Metro, depart from Phoenix Sky Harbor Airport/44th Street Sky Train Station.
Mesa to San Francisco bus services, operated by Valley Metro, arrive at San Francisco Bus Station.
Book your Mesa to San Francisco bus tickets online with Valley Metro, Flixbus USA and Greyhound USA.
The distance between Mesa and San Francisco is 1,072.5 km. The road distance is 1,278 km.
You can take a bus from University Dr & Mesa Dr to San Francisco Bus Station via University Dr & Rural Rd, Tempe, Phoenix Sky Harbor Airport/44th Street Sky Train Station, and Los Angeles Union Station in around 19h 13m.
