The average bus between Mesa and San Luis Obispo takes 17h 29m and the fastest bus takes 17h 27m. The bus runs, on average, 3 times per week from Mesa to San Luis Obispo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a week between Mesa and San Luis Obispo. The earliest departure is at 7:26 PM in the evening, and the last departure from Mesa is at 7:33 PM which arrives into San Luis Obispo at 1:00 PM. All services require a transfer at 24th St/Baseline PNR and take an average of 17h 29m. The schedules shown below are for the next available departures.
Want to know about travelling from Mesa to San Luis Obispo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mesa to San Luis Obispo. However, there are services departing from Mesa station and arriving at San Luis Obispo station via Los Angeles Union Station station. The journey, including transfers, takes approximately 17h 29m.
Mesa to San Luis Obispo bus services, operated by Valley Metro, depart from Phoenix Bus Station.
Mesa to San Luis Obispo bus services, operated by Valley Metro, arrive at San Luis Obispo Railroad Museum station.
The distance between Mesa and San Luis Obispo is 836.9 km. The road distance is 952 km.
You can take a bus from University Dr & Mesa Dr to San Luis Obispo Railroad Museum via 24th St/Baseline PNR, 24th St & Buckeye Rd, Phoenix Bus Station, and Los Angeles Union Station in around 14h 43m.