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Mesa to South Bend buses

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Trip Overview

The bus between Mesa and South Bend takes 2d 21h. The bus runs, on average, once a week from Mesa to South Bend. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 21h
Duration
2,245 mi
Distance
$477
Average price
Once a week
Frequency

Mesa to South Bend bus times

Buses run once a week between Mesa and South Bend. The service departs Mesa at 9:18 PM at night, which arrives into South Bend at 20:50:00. All services require a transfer at University Dr & Rural Rd and take an average of 2d 21h. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

  •  → 

    Arrives +3 days

    Valley MetroFlixbus USAGreyhound USAGreyhound USAGreyhound USAGreyhound USA2d 21h • 5 changes

Frequently asked questions

Want to know about travelling from Mesa to South Bend? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mesa to South Bend.ExpandLaunch map view
  • Distance: 2,244.9 mi
  • Duration: 2d 21h

What companies run services between Mesa, AZ, USA and South Bend, IN, USA?

You can take a bus from University Dr & Mesa Dr to South Bend via University Dr & Rural Rd, Tempe, Phoenix Sky Harbor Airport/44th Street Sky Train Station, El Paso Bus Station, Denver Union Station, and Chicago in around 2d 1h.

Operators