The average bus between Messina and Vatican City takes 10h 37m and the fastest bus takes 9h 48m. The bus service runs several times per day from Messina to Vatican City. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Messina and Vatican City. The earliest departure is at 1:30 AM at night, and the last departure from Messina is at 9:30 PM which arrives into Vatican City at 7:19 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 10h 37m. The schedules shown below are for the next available departures.

10h 41m • 1 change

11h 21m • 1 change
Arrives next day

9h 48m • 1 change

10h 41m • 1 change

11h 21m • 1 change
Arrives next day

9h 58m • 1 change

10h 34m • 1 change

10h 56m • 1 change
Arrives next day

9h 58m • 1 change

10h 34m • 1 change

10h 56m • 1 change
Arrives next day

9h 49m • 1 change
Want to know about travelling from Messina to Vatican City? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Messina to Vatican City. However, there are services departing from Messina station and arriving at Vatican City station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 10h 37m.
Messina to Vatican City bus services, operated by FlixBus, depart from Messina Centrale Station.
Messina to Vatican City bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
Book your Messina to Vatican City bus tickets online with FlixBus and ATAC S.p.A. Azienda per la mobilità.
The distance between Messina and Vatican City is 489.6 km. The road distance is 704 km.
Autoservizi Salemi Srl operates a bus from Messina Centrale Station to Roma, Autostazione Tiburtina twice daily. Tickets cost €28–40 and the journey takes 9h. Itabus S.p.A. also services this route twice daily.