The average bus between Mestre and Brussels takes 17h 47m and the fastest bus takes 16h 55m. The bus service runs several times per day from Mestre to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Mestre and Brussels. The earliest departure is at 2:20 PM in the afternoon, and the last departure from Mestre is at 6:40 PM which arrives into Brussels at 9:35 AM. All services require a transfer, and take on average 17h 47m. The schedules shown below are for the next available departures.
Arrives next day

16h 20m • 1 change
Arrives next day

14h 55m • 1 change
Arrives next day

16h 20m • 1 change
Arrives next day

15h 25m • 1 change
Arrives next day

16h 20m • 1 change
Arrives next day

14h 55m • 1 change
Want to know about travelling from Mestre to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mestre to Brussels. However, there are services departing from Mestre station and arriving at Brussels station via Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 17h 47m.
Mestre to Brussels bus services, operated by FlixBus, depart from Venezia, Viale Stazione (Mestre Stazione - fermata ATVO) station.
Mestre to Brussels bus services, operated by FlixBus, arrive at Brussels-North train station.
Book your Mestre to Brussels bus tickets online with FlixBus.
The distance between Mestre and Brussels is 834.6 km. The road distance is 1,127 km.
You can take a bus from Venezia, Viale Stazione (Mestre Stazione - fermata ATVO) to Brussels-North train station via Milan in around 17h 5m.