The average bus between Mestre and Rome Termini takes 8h 32m and the fastest bus takes 6h 39m. The bus service runs several times per day from Mestre to Rome Termini. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Mestre and Rome Termini. The earliest departure is at 6:50 AM in the morning, and the last departure from Mestre is at 11:50 PM which arrives into Rome Termini at 6:29 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 8h 32m. The schedules shown below are for the next available departures.

8h 26m • 1 change
7h 14m • 1 change
8h 49m • 1 changeArrives next day

12h 8m • 1 change
8h 16m • 1 change
7h 6m • 1 change
8h 52m • 1 changeArrives next day

11h 58m • 1 change
8h 26m • 1 change
7h 9m • 1 change
8h 45m • 1 changeArrives next day

12h 4m • 1 change
8h 26m • 1 change
7h 14m • 1 change
8h 49m • 1 changeArrives next day

12h 5m • 1 change
8h 26m • 1 change
7h 14m • 1 change
8h 49m • 1 changeArrives next day

12h 5m • 1 changeWant to know about travelling from Mestre to Rome Termini? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mestre to Rome Termini. However, there are services departing from Mestre station and arriving at Rome Termini station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 8h 32m.
Mestre to Rome Termini bus services, operated by FlixBus, depart from Venezia, Viale Stazione (Mestre Stazione - fermata ATVO) station.
Mestre to Rome Termini bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
The distance between Mestre and Rome Termini is 399.6 km. The road distance is 524 km.
FlixBus operates a bus from Venezia, Viale Stazione (Mestre Stazione - fermata ATVO) to Roma, Autostazione Tiburtina 4 times a day. Tickets cost €40–70 and the journey takes 6h 40m.