The average bus between Mexico City Airport (MEX) and Acayucan takes 9h 20m and the fastest bus takes 8h 10m. The bus service runs several times per day from Mexico City Airport (MEX) to Acayucan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Mexico City Airport (MEX) and Acayucan. The earliest departure is at 9:30 AM in the morning, and the last departure from Mexico City Airport (MEX) is at 11:55 PM which arrives into Acayucan at 10:35 AM. All services require a transfer at San Lázaro Oriente and take an average of 9h 20m. The schedules shown below are for the next available departures.

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Want to know about travelling from Mexico City Airport (MEX) to Acayucan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mexico City Airport (MEX) to Acayucan. However, there are services departing from Mexico City Airport (MEX) station and arriving at Acayucan station via Acayucan. The journey, including transfers, takes approximately 9h 20m.
Mexico City Airport (MEX) to Acayucan bus services, operated by Metrobús, depart from Terminal de Autobuses de Pasajeros de Oriente station.
Mexico City Airport (MEX) to Acayucan bus services, operated by Metrobús, arrive at Acayucan station.
Book your Mexico City Airport (MEX) to Acayucan bus tickets online with Metrobús and ADO.
The distance between Mexico City Airport (MEX) and Acayucan is 469.2 km. The road distance is 543 km.
ADO operates a bus from Terminal de Autobuses de Pasajeros de Oriente to Acayucan 5 times a day. Tickets cost $1,000–1,600 and the journey takes 8h 5m.