The bus between Mexico City Airport (MEX) and Tlaxcala takes 2h. There is a bus service every few hours from Mexico City Airport (MEX) to Tlaxcala. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Mexico City Airport (MEX) and Tlaxcala. The earliest departure is at 5:40 AM in the morning, and the last departure from Mexico City Airport (MEX) is at 10:50 PM which arrives into Tlaxcala at 12:55 AM. All services require a transfer at Metrobús San Lázaro and take an average of 2h. The schedules shown below are for the next available departures.

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Want to know about travelling from Mexico City Airport (MEX) to Tlaxcala? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mexico City Airport (MEX) to Tlaxcala. However, there are services departing from Mexico City Airport (MEX) station and arriving at Tlaxcala station via Tlaxcala. The journey, including transfers, takes approximately 2h.
Mexico City Airport (MEX) to Tlaxcala bus services, operated by Metrobús, depart from México TAPO station.
Mexico City Airport (MEX) to Tlaxcala bus services, operated by Metrobús, arrive at Tlaxcala station.
The distance between Mexico City Airport (MEX) and Tlaxcala is 93.6 km. The road distance is 122 km.
Autotransportes Tlaxcala, Apizaco, Huamantla, S.A. de C.V. operates a bus from México TAPO to Tlaxcala hourly. Tickets cost $50–270 and the journey takes 1h 30m. Autobuses Supra also services this route hourly.