The average bus between Mexico City and Guatemala takes 7h 3m and the fastest bus takes 6h 30m. There is a bus service every few hours from Mexico City to Guatemala. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Mexico City and Guatemala. The earliest departure is at 12:30 AM at night, and the last departure from Mexico City is at 11:30 PM which arrives into Guatemala at 6:30 AM. All services require a transfer at Nueva Central Camionera de Guadalajara Mod 1 and take an average of 7h 3m. The schedules shown below are for the next available departures.
Arrives next day

7h 18m • 1 change
Arrives next day

7h • 1 change
Arrives next day

7h • 1 change

6h 30m • 1 change

7h • 1 change

7h 2m • 1 change

7h 10m • 1 change

6h 30m • 1 change

7h • 1 change

7h 2m • 1 change

7h 10m • 1 change

6h 30m • 1 change

7h • 1 change

7h 2m • 1 change

7h 10m • 1 change

6h 30m • 1 change

7h • 1 change

7h 2m • 1 change

7h 10m • 1 change
Want to know about travelling from Mexico City to Guatemala? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mexico City to Guatemala. However, there are services departing from Mexico City station and arriving at Guatemala station via Nueva Central Camionera de Guadalajara Mod 1. The journey, including transfers, takes approximately 7h 3m.
Mexico City to Guatemala bus services, operated by Primera Plus, depart from Terminal Central de Autobuses del Norte station.
Mexico City to Guatemala bus services, operated by Primera Plus, arrive at Nueva Central Camionera de Guadalajara Mod 1 station.
The distance between Mexico City and Guatemala is 463.8 km. The road distance is 540 km.
Primera Plus operates a bus from Terminal Central de Autobuses del Norte to Nueva Central Camionera de Guadalajara Mod 1 hourly. Tickets cost $1,300–1,900 and the journey takes 6h 30m.