The bus between Mexico City and Santa Ana takes 2d 2h. There is at least one bus per day from Mexico City to Santa Ana. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Mexico City and Santa Ana. The earliest departure is at 1:00 AM at night, and the last departure from Mexico City is at 1:00 AM which arrives into Santa Ana at 2:30 AM. All services require a transfer, and take on average 2d 2h. The schedules shown below are for the next available departures.
Want to know about travelling from Mexico City to Santa Ana? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mexico City to Santa Ana. However, there are services departing from Mexico City station and arriving at Santa Ana station via Morelia. The journey, including transfers, takes approximately 2d 2h.
Mexico City to Santa Ana bus services, operated by Autovías La Línea, depart from Terminal Poniente - Observatorio station.
Mexico City to Santa Ana bus services, operated by Autovías La Línea, arrive at Santa Ana station.
Book your Mexico City to Santa Ana bus tickets online with Autovías La Línea and ACN Autobuses.
The distance between Mexico City and Santa Ana is 2,443.1 km. The road distance is 3,182 km.
You can take a bus from Terminal Poniente - Observatorio to Santa Ana via Morelia in around 45h 30m.
