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The bus between Mexico City and Santa Ana takes 2d 3h. There is at least one bus per day from Mexico City to Santa Ana. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Mexico City and Santa Ana. The service departs Mexico City at 1:00 AM at night, which arrives into Santa Ana at 02:30:00. All services require a transfer, and take on average 2d 3h. The schedules shown below are for the next available departures.
Want to know about travelling from Mexico City to Santa Ana? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mexico City to Santa Ana. However, there are services departing from Terminal Poniente - Observatorio station and arriving at Santa Ana station via Morelia station. The journey, including transfers, takes approximately 2 days 3h.
Mexico City to Santa Ana bus services, operated by Autovías La Línea, depart from Terminal Poniente - Observatorio station.
Mexico City to Santa Ana bus services, operated by ACN Autobuses, arrive at Santa Ana station.
Book your Mexico City to Santa Ana bus tickets online with Omio.
The distance between Mexico City and Santa Ana is 2443.1 km. The road distance is 2888 km.
You can take a bus from Terminal Poniente - Observatorio to Santa Ana via Morelia in around 45h 30m.
