The average bus between Mexico City and Sisal takes 30h 46m and the fastest bus takes 25h. The bus service runs several times per day from Mexico City to Sisal. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Mexico City and Sisal. The earliest departure is at 5:00 PM in the evening, and the last departure from Mexico City is at 8:00 PM which arrives into Sisal at 9:30 AM. All services require a transfer at Mérida Centro Histórico and take an average of 30h 46m. The schedules shown below are for the next available departures.
Arrives next day


25h • 2 changes
Arrives +2 days


37h 30m • 2 changes
Arrives next day


25h • 2 changes
Arrives +2 days


37h 30m • 2 changes
Arrives next day


25h • 2 changes
Arrives +2 days


37h 30m • 2 changes
Arrives next day


25h • 2 changes
Arrives +2 days


37h 30m • 2 changes
Want to know about travelling from Mexico City to Sisal? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mexico City to Sisal. However, there are services departing from Mexico City station and arriving at Sisal station via Mérida Centro Histórico. The journey, including transfers, takes approximately 30h 46m.
Mexico City to Sisal bus services, operated by ADO, depart from Terminal de Autobuses de Pasajeros de Oriente station.
Mexico City to Sisal bus services, operated by ADO, arrive at Sisal station.
The distance between Mexico City and Sisal is 968 km. The road distance is 1,355 km.
You can take a bus from Terminal de Autobuses de Pasajeros de Oriente to Sisal via Mérida Centro Histórico, C-68 x 67 Col. Centro_1802, R109 C-69 x 58 y 60 Col. Centro_1892, and Mérida Noreste in around 24h 8m.