The average bus between Middle Island and East Setauket takes 2h 5m and the fastest bus takes 1h 17m. There is a bus service every few hours from Middle Island to East Setauket. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Middle Island and East Setauket. The earliest departure is at 5:37 AM in the morning, and the last departure from Middle Island is at 10:38 PM which arrives into East Setauket at 6:17 AM. All services require a transfer, and take on average 2h 5m. The schedules shown below are for the next available departures.

1h 40m • 1 change

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Want to know about travelling from Middle Island to East Setauket? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Middle Island to East Setauket. However, there are services departing from Middle Island station and arriving at East Setauket station via Smith Haven Mall. The journey, including transfers, takes approximately 2h 5m.
Middle Island to East Setauket bus services, operated by Suffolk County Transit, depart from Middle Country Rd/Tudor Ln station.
Middle Island to East Setauket bus services, operated by Suffolk County Transit, arrive at NYS 25A/Old Town Road station.
The distance between Middle Island and East Setauket is 15.5 km. The road distance is 32 km.
You can take a bus from Middle Country Rd/Tudor Ln to NYS 25A/Old Town Road via Smith Haven Mall in around 1h 40m.