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Middleburg to Port Saint Lucie buses

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Trip Overview

The average bus between Middleburg and Port Saint Lucie takes 12h 50m and the fastest bus takes 10h 46m. There is at least one bus per day from Middleburg to Port Saint Lucie. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 50m
Duration
292 mi
Distance
$69
Average price
Once daily
Frequency

Middleburg to Port Saint Lucie bus times

Buses run once daily between Middleburg and Port Saint Lucie. The earliest departure is at 10:14 AM in the morning, and the last departure from Middleburg is at 5:19 PM which arrives into Port Saint Lucie at 8:45 AM. All services require a transfer at Blanding Blvd + Orange Park Northway and take an average of 12h 50m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

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    Arrives next day

    Jacksonville TransportJacksonville TransportFlixbus USALynx Central Florida TransportLynx Central Florida TransportJet Set Express15h 26m • 5 changes

Departing Friday, November 13, 2026

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    Jacksonville TransportJacksonville TransportFlixbus USALynx Central Florida TransportLynx Central Florida TransportJet Set Express10h 46m • 5 changes
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    Arrives next day

    Jacksonville TransportJacksonville TransportFlixbus USALynx Central Florida TransportLynx Central Florida TransportJet Set Express15h 26m • 5 changes

Departing Monday, November 16, 2026

  •  → 

    Jacksonville TransportJacksonville TransportFlixbus USALynx Central Florida TransportLynx Central Florida TransportJet Set Express10h 46m • 5 changes
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    Arrives next day

    Jacksonville TransportJacksonville TransportFlixbus USALynx Central Florida TransportLynx Central Florida TransportJet Set Express15h 26m • 5 changes

Departing Tuesday, November 17, 2026

  •  → 

    Jacksonville TransportJacksonville TransportFlixbus USALynx Central Florida TransportLynx Central Florida TransportJet Set Express10h 46m • 5 changes
  •  → 

    Arrives next day

    Jacksonville TransportJacksonville TransportFlixbus USALynx Central Florida TransportLynx Central Florida TransportJet Set Express15h 26m • 5 changes

Departing Wednesday, November 18, 2026

  •  → 

    Jacksonville TransportJacksonville TransportFlixbus USALynx Central Florida TransportLynx Central Florida TransportJet Set Express10h 46m • 5 changes

Frequently asked questions

Want to know about travelling from Middleburg to Port Saint Lucie? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Middleburg to Port Saint Lucie.ExpandLaunch map view
  • Distance: 292.4 mi
  • Duration: 12h 50m

What companies run services between Middleburg, FL, USA and Port Saint Lucie, FL, USA?

You can take a bus from Wells Fargo to Fort Pierce via Blanding Blvd + Orange Park Northway, JRTC Bay P, Jacksonville, Orlando Bus Station, John Young Pkwy & Amelia St, N Garland Ave & W Amelia St, L B Mcleod Rd & Gardenia Ave, and Orlando in around 9h 34m.

Operators