- Distance: 460.9 mi
- Duration: 8h 35m
The average bus between Midtown Manhattan and Buffalo takes 8h 35m and the fastest bus takes 8h. The bus service runs several times per day from Midtown Manhattan to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Midtown Manhattan and Buffalo. The earliest departure is at 5:15 AM in the morning, and the last departure from Midtown Manhattan is at 11:59 PM which arrives into Buffalo at 8:45 AM. All services run direct with no transfers required, and take on average 8h 35m. The schedules shown below are for the next available departures.
Arrives next day
Arrives next day
Want to know about travelling from Midtown Manhattan to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Midtown Manhattan station and arriving at Buffalo station. Services depart every 4 hours, and operate Twice daily. The journey takes approximately 8h 35m.
Midtown Manhattan to Buffalo bus services, operated by Trailways, depart from New York station.
Midtown Manhattan to Buffalo bus services, operated by Trailways, arrive at Buffalo station.
Book your Midtown Manhattan to Buffalo bus tickets online with Trailways and Flixbus USA.
The distance between Midtown Manhattan and Buffalo is 469.9 km. The road distance is 742 km.
Trailways operates a bus from New York to Buffalo every 4 hours. Tickets cost $60–280 and the journey takes 8h. Flixbus USA also services this route every 4 hours.
