Rome2Rio

Milan Cathedral to Roma Termini buses

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Trip Overview

The average bus between Milan Cathedral and Roma Termini takes 12h 41m and the fastest bus takes 9h 24m. There is at least one bus per day from Milan Cathedral to Roma Termini. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 41m
Duration
600 km
Distance
€70
Average price
Once daily
Frequency

Milan Cathedral to Roma Termini bus times

Buses run once daily between Milan Cathedral and Roma Termini. The earliest departure is at 5:19 AM in the morning, and the last departure from Milan Cathedral is at 6:19 AM which arrives into Roma Termini at 3:43 PM. All services require a transfer at duomo m1 m3 and take an average of 12h 41m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

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    ATMFlixBusATAC S.p.A. Azienda per la mobilità10h 8m • 2 changes

Departing Saturday, November 7, 2026

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    ATMFlixBusATAC S.p.A. Azienda per la mobilità10h 27m • 2 changes

Departing Sunday, November 8, 2026

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    ATMFlixBusATAC S.p.A. Azienda per la mobilità9h 24m • 2 changes

Departing Monday, November 9, 2026

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    ATMFlixBusATAC S.p.A. Azienda per la mobilità10h 8m • 2 changes

Departing Tuesday, November 10, 2026

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    ATMFlixBusATAC S.p.A. Azienda per la mobilità11h 20m • 2 changes

Departing Wednesday, November 11, 2026

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    ATMFlixBusATAC S.p.A. Azienda per la mobilità11h 20m • 2 changes

Departing Thursday, November 12, 2026

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    ATMFlixBusATAC S.p.A. Azienda per la mobilità11h 20m • 2 changes

Frequently asked questions

Want to know about travelling from Milan Cathedral to Roma Termini? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Milan Cathedral to Roma Termini.ExpandLaunch map view
  • Distance: 599.8 km
  • Duration: 12h 41m

What companies run services between Milan Cathedral, Lombardy, Italy and Roma Termini, Italy?

FlixBus operates a bus from Milano, San Donato M3 to Roma, Autostazione Tiburtina every 2 hours. Tickets cost €50–80 and the journey takes 7h 30m.

Operators