The average bus between Milan and Brienno takes 3h 15m and the fastest bus takes 1h 26m. The bus service runs several times per day from Milan to Brienno. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Milan and Brienno. The earliest departure is at 7:10 AM in the morning, and the last departure from Milan is at 11:05 PM which arrives into Brienno at 6:55 AM. All services require a transfer, and take on average 3h 15m. The schedules shown below are for the next available departures.

2h 11m • 1 change

1h 26m • 1 change
Arrives next day

6h 46m • 1 change

2h 11m • 1 change

1h 26m • 1 change
Arrives next day

6h 46m • 1 change

2h 11m • 1 change

1h 26m • 1 change
Arrives next day

6h 46m • 1 change
Want to know about travelling from Milan to Brienno? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Milan to Brienno. However, there are services departing from Milan station and arriving at Brienno station via Como. The journey, including transfers, takes approximately 3h 15m.
Milan to Brienno bus services, operated by FlixBus, depart from Milano, Autostazione Lampugnano station.
Milan to Brienno bus services, operated by FlixBus, arrive at Brienno station.
The distance between Milan and Brienno is 49.9 km. The road distance is 151 km.
You can take a bus from Milano, Autostazione Lampugnano to Brienno via Como San Giovanni in around 2h 21m.